MIRD Pamphlet No. 24: Guidelines for Quantitative I-131 SPECT in Dosimetry Applications

Summary, in English

The reliability of radiation dose estimates in internal radionuclide therapy is directly related to the accuracy of activity estimates obtained at each imaging time point. The recently published MIRD pamphlet no. 23 provided a general overview of quantitative SPECT imaging for dosimetry. The present document is the first in a series of isotope-specific guidelines that will follow MIRD 23 and focuses on one of the most commonly used therapeutic radionuclides, I-131. The purpose of this document is to provide guidance on the development of protocols for quantitative I-131 SPECT in radionuclide therapy applications that require regional (normal organs, lesions) and 3-dimensional dosimetry.

• Författare: Yuni K. Dewaraja; Michael Ljungberg; Alan J. Green; Pat B. Zanzonico; Eric C. Frey
• Avdelning/ar: Medicinsk strålningsfysik, Lund
• Publiceringsår: 2013
• Språk: Engelska
• Sidor: 2182-2188
• Publikation/Tidskrift/Serie: Journal of Nuclear Medicine
• Volym: 54
• Issue: 12
• Länkar: http://dx.doi.org/10.2967/jnumed.113.122390
• Dokumenttyp: Artikel i tidskrift
• Förlag: Society of Nuclear Medicine
• Ämne: Radiology, Nuclear Medicine and Medical Imaging
• Nyckelord: MIRD; I-131; quantitative SPECT; SPECT/CT; dosimetry
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 0161-5505