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Crister Ceberg

Professor

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A clinical distance measure for evaluating treatment plan quality difference with Pareto fronts in radiotherapy

Författare

  • Kristoffer Petersson
  • Archonteia Kyroudi
  • Jean Bourhis
  • Crister Ceberg
  • Tommy Knoos
  • Francois Bochud
  • Raphaël Möckli

Summary, in English

We present a clinical distance measure for Pareto front evaluation studies in radiotherapy, which we show strongly correlates (r = 0.74 and 0.90) with clinical plan quality evaluation. For five prostate cases, sub-optimal treatment plans located at a clinical distance value of >0.32 (0.28–0.35) from fronts of Pareto optimal plans, were assessed to be of lower plan quality by our (12) observers (p < .05). In conclusion, the clinical distance measure can be used to determine if the difference between a front and a given plan (or between different fronts) corresponds to a clinically significant plan quality difference.

Avdelning/ar

  • Medicinsk strålningsfysik, Lund
  • Radiotherapy Physics
  • Rausinglaboratoriet i Lund - Tumörsektionen

Publiceringsår

2017-07

Språk

Engelska

Sidor

53-56

Publikation/Tidskrift/Serie

Physics and imaging in radiation oncology

Volym

3

Dokumenttyp

Artikel i tidskrift

Förlag

Elsevier

Ämne

  • Radiology, Nuclear Medicine and Medical Imaging
  • Other Physics Topics

Status

Published

Forskningsgrupp

  • Radiotherapy Physics
  • Rausing laboratory of Lund - Tumor section

ISBN/ISSN/Övrigt

  • ISSN: 2405-6316