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Ceberg

Crister Ceberg

Professor

Ceberg

Quality assurance of patient dosimetry in boron neutron capture therapy

Författare

  • Per Munck af Rosenschöld
  • Jacek Capala
  • Crister Ceberg
  • Valerio Giusti
  • Leif Salford
  • Bertil R Persson

Summary, in English

The verification of the correctness of planned and executed treatments is imperative for safety in radiotherapy. The purpose of the present work is to describe and evaluate the quality assurance (QA) procedures for patient dosimetry implemented at the boron neutron capture therapy (BNCT) facility at Studsvik, Sweden. The dosimetric complexity of the mixed neutron-photon field during BNCT suggests a careful verification of routine procedures, specifically the treatment planning calculations. In the present study, two methods for QA of patient dosimetry are presented. The first is executed prior to radiotherapy and involves an independent check of the planned absorbed dose to be delivered to a point in the patient for each treatment field. The second QA procedure involves in vivo dosimetry measurements using posttreatment activation analysis. Absorbed dose conversion factors taking the difference in material composition and geometry of the patient and the PMMA phantom used for reference dosimetry were determined using the Monte Carlo method. The agreement of the QA procedure prior to radiotherapy reveals an acceptably small deviation for 60 treatment fields of ±4.2% (1 SD), while the in vivo dosimetry method presented may benefit from improvements, as the deviations observed were quite substantial (±12%, 1 SD), and were unlikely to be due to actual errors in the clinical dosimetry.

Avdelning/ar

  • Medicinsk strålningsfysik, Lund
  • Neurokirurgi

Publiceringsår

2004

Språk

Engelska

Sidor

404-411

Publikation/Tidskrift/Serie

Acta Oncologica

Volym

43

Issue

4

Dokumenttyp

Artikel i tidskrift

Förlag

Taylor & Francis

Ämne

  • Cancer and Oncology

Nyckelord

  • Sensitivity and Specificity
  • Support
  • Boron Neutron Capture Therapy: methods
  • Non-U.S. Gov't
  • Human
  • Monte Carlo Method
  • Radiotherapy Dosage
  • Radiotherapy Planning
  • Radiation
  • Radiation Monitoring
  • Imaging
  • Radiation Injuries: prevention & control
  • Quality Control
  • Computer-Assisted
  • Phantoms
  • Comparative Study
  • Brain Neoplasms: radiotherapy
  • Dose-Response Relationship

Status

Published

ISBN/ISSN/Övrigt

  • ISSN: 1651-226X