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Freddy Ståhlberg

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Separation of arteries and veins using flow-induced phase effects in contrast-enhanced MRA of the lower extremities

Författare

  • Jonas Svensson
  • Peter Leander
  • Jeffrey H Maki
  • Freddy Ståhlberg
  • Lars E Olsson

Summary, in English

In 3-D contrast-enhanced magnetic resonance (MR) angiography of the lower extremities the goal is most often to enhance arterial structures while keeping veins and surrounding tissue unenhanced. Imaging during steady-state concentration of a blood pool agent or during poor timing of an extra-cellular contrast medium may result in simultaneous venous enhancement, making interpretation of the angiogram difficult. The aim of this study was to develop a post-processing method to separate the arteries from the veins in standard contrast-enhanced MR angiograms. The method was based on the different accumulation of flow-induced phase in the arteries and veins of the lower extremities. The method was tested in both phantom experiments and volunteers undergoing 3-D contrast-enhanced MR angiography using both an extra-cellular contrast medium and a blood pool agent. In the phantom studies, opposite directional flow was successfully separated at mean flow velocities as low as 9 cm/s. In the volunteer studies, the larger veins were successfully extinguished while the larger arteries were left unaffected. In smaller vessels with low flow velocities the separation was less successful. This was most apparent in vessels not oriented superior-inferior. The method developed here is promising for separating arteries from veins in contrast-enhanced MR angiography although the results could be further improved by either a different pulse sequence design or combining this method with other segmentation methods.

Avdelning/ar

  • Medicinsk strålningsfysik, Malmö
  • Diagnostisk radiologi, Malmö
  • Medicinsk strålningsfysik, Lund

Publiceringsår

2002-01

Språk

Engelska

Sidor

49-57

Publikation/Tidskrift/Serie

Magnetic Resonance Imaging

Volym

20

Issue

1

Dokumenttyp

Artikel i tidskrift

Förlag

Elsevier

Ämne

  • Radiology, Nuclear Medicine and Medical Imaging

Nyckelord

  • Arteries
  • Blood Flow Velocity
  • Contrast Media
  • Humans
  • Image Processing, Computer-Assisted
  • Imaging, Three-Dimensional
  • Leg
  • Magnetic Resonance Angiography
  • Models, Theoretical
  • Phantoms, Imaging
  • Veins

Status

Published

Forskningsgrupp

  • Medical Radiation Physics, Malmö
  • Radiology Diagnostics, Malmö

ISBN/ISSN/Övrigt

  • ISSN: 0730-725X