Webbläsaren som du använder stöds inte av denna webbplats. Alla versioner av Internet Explorer stöds inte längre, av oss eller Microsoft (läs mer här: * https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Var god och använd en modern webbläsare för att ta del av denna webbplats, som t.ex. nyaste versioner av Edge, Chrome, Firefox eller Safari osv.

Default user image.

Linda Knutsson

Professor

Default user image.

Cerebral perfusion imaging in hemodynamic stroke: be aware of the pattern.

Författare

  • Roger Siemund
  • Mats Cronqvist
  • Gunnar Andsberg
  • Birgitta Ramgren
  • Linda Knutsson
  • Stig Holtås

Summary, in English

Summary: Reduction of the cerebral perfusion pressure caused by vessel occlusion or stenosis is a cause of neurological symptoms and border-zone infarctions. The aim of this article is to describe perfusion patterns in hemodynamic stroke, to give a practical approach for the assessment of colour encoded CT- and MR-perfusion maps and to demonstrate the clinical use of comprehensive imaging in the workup of patients with hemodynamic stroke. Five patients with different duration cause and degree of hemodynamic stroke were selected. The patients shared the typical presentation with fluctuating and transient symptoms. All were examined by MR or CT angiography and MR or CT perfusion in the symptomatic phase. All patients were examined with diffusion weighted imaging. All five cases showed the altered perfusion patterns of hemodynamic insufficiency with a slight or marked increase in CBV in the supply area of the affected vessel and only slightly reduced or maintained CBF. The perfusion disturbances were most easily detected on the MTT maps. Border-zone infarctions were seen in all cases. The typical pattern for hemodynamic insufficiency is characterized by increased CBV, normal or decreased CBF and prolonged MTT in the affected areas. The increased CBV is the hallmark of stressed autoregulation. Reading the color-encoded perfusion maps enables a quick and robust assessment of the cerebral perfusion and its characteristic patterns. Internal border-zone infarctions can be regarded as a marker for hemodynamic insufficiency. Finding of the typical rosary-like pattern of DWI lesions should call for further work up.

Avdelning/ar

  • Diagnostisk radiologi, Lund
  • Neurologi, Lund
  • Medicinsk strålningsfysik, Lund
  • MR Physics

Publiceringsår

2009

Språk

Engelska

Sidor

385-394

Publikation/Tidskrift/Serie

Interventional Neuroradiology

Volym

15

Issue

4

Dokumenttyp

Artikel i tidskrift

Förlag

Centauro srl

Ämne

  • Radiology, Nuclear Medicine and Medical Imaging

Status

Published

Projekt

  • Optimisation and Validation of Dynamic Susceptibility Contrast MRI

Forskningsgrupp

  • MR Physics

ISBN/ISSN/Övrigt

  • ISSN: 1591-0199