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Linda Knutsson

Professor

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Consensus statement on current and emerging methods for the diagnosis and evaluation of cerebrovascular disease

Författare

  • Manus J Donahue
  • Eric Achten
  • Petrice M Cogswell
  • Frank-Erik De Leeuw
  • Colin P Derdeyn
  • Rick M Dijkhuizen
  • Audrey P Fan
  • Rashid Ghaznawi
  • Jeremy J Heit
  • M Arfan Ikram
  • Peter Jezzard
  • Lori C Jordan
  • Eric Jouvent
  • Linda Knutsson
  • Richard Leigh
  • David S Liebeskind
  • Weili Lin
  • Thomas W Okell
  • Adnan I Qureshi
  • Charlotte J Stagg
  • Matthias Jp van Osch
  • Peter Cm van Zijl
  • Jennifer M Watchmaker
  • Max Wintermark
  • Ona Wu
  • Greg Zaharchuk
  • Jinyuan Zhou
  • Jeroen Hendrikse
Visa allt

Summary, in English

Cerebrovascular disease (CVD) remains a leading cause of death and the leading cause of adult disability in most developed countries. This work summarizes state-of-the-art, and possible future, diagnostic and evaluation approaches in multiple stages of CVD, including (i) visualization of sub-clinical disease processes, (ii) acute stroke theranostics, and (iii) characterization of post-stroke recovery mechanisms. Underlying pathophysiology as it relates to large vessel steno-occlusive disease and the impact of this macrovascular disease on tissue-level viability, hemodynamics (cerebral blood flow, cerebral blood volume, and mean transit time), and metabolism (cerebral metabolic rate of oxygen consumption and pH) are also discussed in the context of emerging neuroimaging protocols with sensitivity to these factors. The overall purpose is to highlight advancements in stroke care and diagnostics and to provide a general overview of emerging research topics that have potential for reducing morbidity in multiple areas of CVD.

Avdelning/ar

  • Medicinsk strålningsfysik, Lund
  • MR Physics

Publiceringsår

2018

Språk

Engelska

Sidor

1391-1417

Publikation/Tidskrift/Serie

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Volym

38

Issue

9

Dokumenttyp

Artikel i tidskrift

Förlag

Nature Publishing Group

Ämne

  • Neurology
  • Other Physics Topics

Nyckelord

  • Journal Article

Status

Published

Projekt

  • Optimisation and Validation of Dynamic Susceptibility Contrast MRI

Forskningsgrupp

  • MR Physics

ISBN/ISSN/Övrigt

  • ISSN: 1559-7016