Polymer gel dosimetry for experimental verification of conformal small animal irradiation at a preclinical research platform

Summary, in English

In translational research, there is a need for preclinical studies of high quality that corresponds to the conformal dose distributions conventionally delivered to humans in the modern radiotherapy clinic. To facilitate this need, novel preclinical systems consist of preclinical radiation platforms and small animal treatment planning systems. However, small-field dosimetry is challenging and requires dosimeters with high spatial resolution. In this study we demonstrate the feasibility of experimentally validating the dose distribution in small fields at a preclinical X-ray research platform using a polymer gel dosimeter and MRI-readout.

• Författare: E. Konradsson; M. Blomstedt; C. Jamtheim Gustafsson; S. Å.J. Bäck; C. Ceberg; S. Ceberg
• Avdelning/ar: Radiotherapy Physics; Medicinsk strålningsfysik, Lund; Medicinsk strålningsfysik, Malmö; LUCC: Lunds universitets cancercentrum; Rausinglaboratoriet i Lund - Tumörsektionen
• Publiceringsår: 2023
• Språk: Engelska
• Publikation/Tidskrift/Serie: Journal of Physics: Conference Series
• Volym: 2630
• Issue: 1
• Länkar: http://dx.doi.org/10.1088/1742-6596/2630/1/012034
• Dokumenttyp: Artikel i tidskrift
• Förlag: IOP Publishing
• Ämne: Radiology, Nuclear Medicine and Medical Imaging
• Conference name: 12th International Conference on 3D and Advanced Dosimetry, IC3DDose 2022
• Conference date: 2022-07-19 - 2022-07-22
• Conference place: Quebec City, Canada
• Status: Published
• Forskningsgrupp: Radiotherapy Physics; Medical Radiation Physics, Malmö; Rausing laboratory of Lund - Tumor section
• ISBN/ISSN/Övrigt: ISSN: 1742-6596