Fourier analysis of cerebrospinal fluid flow velocities : MR imaging study

Summary, in English

An interleaved pseudocinematographic FLASH (fast low-angle shot) sequence with additional pulsed gradients for flow encoding was used to quantify cerebrospinal fluid (CSF) flow velocities and CSF production. Flow-dependent phase information was obtained by subtracting two differently encoded phase images. The phase information in the resultant image was converted to flow velocity with a calibration curve with the slope 26.5 radian · m^-1 · sec. The velocity versus time function was Fourier transformed and a continuous curve was fitted to the measured data with use of the first three harmonics. The in vivo measurements showed a significant variation in flow velocities in the cerebral aqueduct (range, 6-51 mm/ sec). Calculated CSF production was in the range of 0.6-1.2 L/24 h. The present method gives valuable information about CSF hydrodynamics in an imaging time of less than 8 minutes.

• Författare: Carsten Thomsen; Freddy Ståhlberg; M. Stubgaard; Bo Nordell
• Avdelning/ar: MR Physics; Medicinsk strålningsfysik, Lund; Diagnostisk radiologi, Lund
• Publiceringsår: 1990-12
• Språk: Engelska
• Sidor: 659-665
• Publikation/Tidskrift/Serie: Radiology
• Volym: 177
• Issue: 3
• Länkar: http://dx.doi.org/10.1148/radiology.177.3.2243965
• Dokumenttyp: Artikel i tidskrift
• Förlag: Radiological Society of North America
• Ämne: Radiology, Nuclear Medicine and Medical Imaging
• Nyckelord: Cerebrospinal fluid, flow dynamics, 10.1214; Cerebrospinal fluid, MR studies, 10.1214; Magnetic resonance (MR), physics; Magnetic resonance (MR), pulse sequences; Phantoms
• Status: Published
• Forskningsgrupp: MR Physics
• ISBN/ISSN/Övrigt: ISSN: 0033-8419