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Ronnie Wirestam

Professor

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Magnetization transfer (MT) of human brain at 7T in the context of a 3D multi-parameter mapping protocol

Författare

  • Hampus Olsson
  • Mads Andersen
  • Jimmy Lätt
  • Ronnie Wirestam
  • Gunther Helms

Summary, in English

3D multi-gradient echo MRI can be used to estimate T1, T2*, PD and the magnetization transfer (MT), which is increasingly used for multi-parametric
mapping (MPM) of human brain. The increased polarization at 7T compared to lower B0 allows for increased spatial resolution or reduced scan
times. However, SAR restrictions imposed on the MT pulse and B1 inhomogeneity pose challenges. In this work, we propose a protocol for MPM of
human brain at 7T with special attention paid to eliminating bias when mapping MT saturation while obtaining sub-millimeter isotropic spatial resolution in
under 12 minutes with acceptable SNR.

Avdelning/ar

  • Medicinsk strålningsfysik, Lund
  • MR Physics

Publiceringsår

2019-04-29

Språk

Engelska

Publikation/Tidskrift/Serie

Proc Intl Soc Magn Reson Med

Volym

27

Dokumenttyp

Konferensbidrag

Förlag

International Society for Magnetic Resonance in Medicine

Ämne

  • Medical and Health Sciences
  • Other Physics Topics

Conference name

ISMRM 27th Annual Meeting and Exhibition

Conference date

2019-05-11 - 2019-05-16

Conference place

Montreal, Canada

Status

Published

Projekt

  • Multiparametric mapping of the brain at 7T using gradient echoes

Forskningsgrupp

  • MR Physics

ISBN/ISSN/Övrigt

  • ISSN: 1545-4428